A Guide to Benefits, Risks, and What to Expect from IV Iron Therapy

If you've ever been told you have low iron levels or iron-deficiency anemia, chances are you’ve heard about iron supplements. But what happens when oral supplements just don’t cut it? That’s where iron infusions come in, a powerful option for replenishing your iron stores quickly and effectively.
What are Iron Infusions?
An iron infusion is a procedure where iron is delivered directly into your bloodstream through an IV. It’s typically used when:
- Oran iron supplements haven’t worked or caused side effects like a nausea or constipation
- You need iron urgently due to severe anemia
- You have a condition that affects how your body absorbs iron (e.g. Crohn’s disease, celiac disease, chronic kidney disease)
- You're pregnant and oral iron isn’t enough
The Process: What to Expect
Iron infusions are usually given in a hospital or clinic setting and can take anywhere from 15 minutes to several hours, depending on the type and dose of iron used.
- Prep: a nurse will check your vitals and start an IV line.
- Infusion: the iron solution is administered slowly to reduce the risk of side effects.
- Monitoring: you’ll be monitored during and after the infusion for any allergic reactions or other responses.
- Post-infusion: most people can go home the same day and resume normal activities shortly after.
How Will I Feel After?
Everyone reacts differently. Some people feel more energized within a few days, while for others, it might take a couple of weeks. A boost in iron means your body can make more red blood cells, so more oxygen gets delivered to your tissues, making you feel less fatigued, less dizzy, and more like yourself again.
Are There Side Effects?
Most people tolerate iron infusions well, but like any medical treatment, there are potential side effects:
- Mild: headache, metallic taste, nausea, or flu-like symptoms
- Rare but serious: allergic reactions or low blood pressure during the infusion
Your healthcare team will be prepared to manage any adverse effects right away.
Is It Right for You?
If you’re struggling with fatigue, pale skin, brittle nails, or frequent shortness of breath, and oral iron hasn’t helped, talk to your doctor about testing your ferritin and hemoglobin levels. An iron infusion might be the solution to get your energy back on track.